Immune System - the Bodys Natural Defense Mechanism

Immune System - the Body's Natural Defense Mechanism Immune System Function Theres a mantra in organized sports that says, defense is king! In todays world, with germs lurking around every corner, it pays to have a strong defense. The immune system is the bodys natural defense mechanism. The function of this system is to prevent or reduce the occurrence of infection. This is accomplished through the coordinated function of the bodys immune cells. Cells of the immune system, known as  white blood cells,  are found in our bone marrow, lymph nodes, spleen, thymus, tonsils, and in the liver of embryos. When microorganisms, such as bacteria or viruses invade the body, non-specific defense mechanisms provide the first line of defense. Key Takeaways The immune system is the bodys natural defense mechanism whose function is to help fight infections.The innate immune system is a non-specific response that includes deterrents like the skin, enzymes in saliva, and inflammatory reactions by immune cells.If organisms get past the innate immune system, the adaptive immune system is the backup system. This backup system is a specific response to specific pathogens.The adaptive immunity system has two primary components: a humoral immune response and a cell mediated immune response.Disorders and diseases that can result from a compromised immune system include: allergies, HIV/AIDS and rheumatoid arthritis. Innate Immune System The innate immune system is a non-specific response that includes primary deterrents. These deterrents ensure protection against numerous germs and parasitic pathogens (fungi, nematodes, etc.). There are physical deterrents (skin and nasal hairs), chemical deterrents (enzymes found in perspiration and saliva), and inflammatory reactions (initiated by immune cells). These particular mechanisms are named appropriately because their responses are not specific to any particular pathogen. Think of these as a perimeter alarm system in a house. No matter who trips the motion detectors, the alarm will sound. White blood cells involved in the innate immune response include macrophages, dendritic cells, and granulocytes (neutrophils, eosinophils, and basophils). These cells respond immediately to threats and are also involved in the activation of adaptive immune cells. Adaptive Immune System In cases where microorganisms get through the primary deterrents, there is a backup system called the adaptive immune system. This system is a specific defense mechanism in which immune cells respond to specific pathogens and also provide protective immunity. Like innate immunity, adaptive immunity includes two components: a humoral immune response and a cell mediated immune response. Humoral Immunity The humoral immune response or antibody†mediated response  protects against bacteria and viruses present in the fluids of the body. This system uses white blood cells called B cells, which have the ability to recognize organisms that dont belong to the body. In other words, if this isnt your house, get out! Intruders are referred to as antigens. B cell lymphocytes produce antibodies that recognize and bind to a specific antigen to identify it as an invader that needs to be terminated. Cell Mediated Immunity The cell mediated immune response protects against foreign organisms that have managed to infect body cells. It also protects the body from itself by controlling cancerous cells. White blood cells involved in cell mediated immunity include macrophages, natural killer (NK) cells, and T cell lymphocytes. Unlike B cells, T cells are actively involved with the disposal of antigens. They make proteins called T cell receptors that help them recognize a specific antigen. There are three classes of T cells that play specific roles in the destruction of antigens: Cytotoxic T cells (which directly terminate antigens), Helper T cells (which precipitate the production of antibodies by B cells), and Regulatory T cells (which suppress the response of B cells and other T cells). Immune Disorders There are serious consequences when the immune system is compromised. Three known immune disorders are allergies, severe combined immunodeficiency (T and B cells are not present or functional), and HIV/AIDS (severe decrease in the number of Helper T cells). In cases involving autoimmune disease, the immune system attacks the bodys own normal tissues and cells. Examples of autoimmune disorders include multiple sclerosis (affects the central nervous system), rheumatoid arthritis (affects joints and tissues), and graves disease (affects the thyroid gland). Lymphatic System The lymphatic system is a component of the immune system that is responsible for the development and circulation of immune cells, specifically lymphocytes. Immune cells are produced in bone marrow. Certain types of lymphocytes migrate from bone marrow to lymphatic organs, such as the spleen and thymus, to mature into fully functioning lymphocytes. Lymphatic structures filter blood and lymph of microorganisms, cellular debris, and waste.

Decker Surname Origin and Family History

Decker Surname Origin and Family History The  Decker surname most commonly originated as an occupational surname for a roofer or thatcher, derived from the Old High German word decker, meaning one who covered roofs with tile, straw or slate. The meaning of the word expanded during the Middle Ages to encompass carpenters and other craftsman and was used to refer to one who built or laid the decks of vessels.  The popular Dutch surname Dekker has the same meaning, derived from the Middle Dutch  deck(e)re, from  decken, meaning to cover. The Decker surname may also derive from the German decher, meaning the quantity of ten; this may also have been a name given to the tenth child. Alternate Surname Spellings: DEKER, DECKER, DECHER, DECKARD, DECHARD, DEKKER, DEKKES, DEKK, DECK, DECKERT Surname Origin: German, Dutch Where in the World Is the Decker Surname Found? According to World Names PublicProfiler, the Decker surname is the most commonly found, based on percentage of population, in Newfoundland and Labrador, Canada. It is also a very popular surname in the countries of Luxembourg and Germany. The Forbears surname distribution map for 2014 identifies the Decker surname as being very popular in Sierra Leone, based on frequency distribution. Famous People With the Decker Surname Jessie James Decker -  American country pop singer-songwriter and reality T.V. personalityEric Decker - American National League Football wide receiverDesmond Dekker - Jamaican  singer-songwriter and musicianThomas Dekker -  English  dramatist and pamphlet writer Genealogy Resources for the Surname DECKER Decker Family Genealogy Forum - Search this popular genealogy forum for the Decker surname to find others who might be researching your ancestors, or post your own Decker surname query.FamilySearch - DECKER Genealogy - Explore over 1.3 million results, including digitized records, database entries, and online family trees for the Decker surname and its variations on the FREE FamilySearch website, courtesy of the Church of Jesus Christ of Latter-day Saints.GeneaNet - Decker Records - GeneaNet includes archival records, family trees, and other resources for individuals with the Decker surname, with a concentration on records and families from France and other European countries.Ancestry.com: Decker  Surname - Explore over 2.4  million digitized records and database entries, including census records, passenger lists, military records, land deeds, probates, wills and other records for the Decker surname on the subscription-based website, Ancestry.com Resources and Further Reading Cottle, Basil.  Penguin Dictionary of Surnames. Baltimore, MD: Penguin Books, 1967.Dorward, David.  Scottish Surnames. Collins Celtic (Pocket edition), 1998.Fucilla, Joseph.  Our Italian Surnames. Genealogical Publishing Company, 2003.Hanks, Patrick and Flavia Hodges.  A Dictionary of Surnames. Oxford University Press, 1989.Hanks, Patrick.  Dictionary of American Family Names. Oxford University Press, 2003.Reaney, P.H.  A Dictionary of English Surnames. Oxford University Press, 1997.Smith, Elsdon C.  American Surnames. Genealogical Publishing Company, 1997.